Thursday, February 2, 2012

Birth control pills recalled, may not prevent pregnancy (Reuters)

(Reuters) ? Pfizer Inc said on Tuesday it was recalling about 1 million packets of birth control pills in the United States because they may not contain enough contraceptive to prevent pregnancy.

Pfizer said the birth control pills posed no health threat to women but it urged consumers affected by the recall to "begin using a non-hormonal form of contraception immediately."

The drugmaker said the issue involved 14 lots of Lo/Ovral-28 tablets and 14 lots of Norgestrel and Ethinyl Estradiol tablets.

It said an investigation had found that some blister packs of the oral contraceptive might contain an inexact count of inert or active ingredients in the tablets.

The pills were manufactured by Pfizer and marketed by Akrimax Pharmaceuticals and shipped to warehouses, clinics and retail pharmacies nationwide, the company said.

(Reporting by James Kelleher; Editing by Greg McCune and Carol Bishopric)

Source: http://us.rd.yahoo.com/dailynews/rss/parenting/*http%3A//news.yahoo.com/s/nm/20120201/hl_nm/us_birthcontrol_recall

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CIA chief says appears Saudi oil "ramping up" (Reuters)

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Medivation prostate cancer drug well-tolerated in trial (Reuters)

(Reuters) ? Medivation Inc's experimental prostate cancer pill caused fewer serious side effects in clinical trial patients than a placebo treatment, according to full results from a pivotal study announced on Tuesday.

The news sent shares of Medivation up more than 11 percent to $61.75 in after-hours trading.

Medivation and partner Astellas Pharma Inc reported in November that the trial had been stopped early after it became clear that the drug, MDV3100, improved median overall survival by 4.8 months compared with a placebo.

Researchers said the trial of 1,199 patients with advanced prostate cancer showed that serious side effects occurred in 28.4 percent of MDV3100 patients, compared with 33.6 percent of the placebo group.

Five patients, or 0.6 percent of the treated group, experienced seizures, said Dr. Howard Scher of Memorial Sloan-Kettering Cancer Center in New York, the trial's lead investigator. An earlier trial of MDV3100 found that 1.5 percent of 198 treated patients had seizures, and some observers were concerned about the drug's safety profile.

The results will likely position MDV3100 as the first treatment for use after patients have stopped responding to chemotherapy, according to Scher. The drug is also being tested in patients with earlier-stage prostate cancer.

The safety profile of the drug "looked good with no major red flags," said ISI Group analyst Mark Schoenebaum, adding that the seizure rate "could pose some concern as the drug is developed in earlier stages of disease."

The full trial results will be presented this week in San Francisco at a meeting sponsored by the American Society of Clinical Oncology.

Dr. Nicholas Vogelzang, an oncologist at the Comprehensive Cancer Centers of Nevada and chair of ASCO's communications committee, described the Medivation trial results as "unprecedented," adding "this is going to definitely change the way we take care of patients every day in the office." He was not involved in the study.

MDV3100 is one of a new class of drugs, known as androgen inhibitors, designed to interfere with the ability of testosterone to bind to prostate cancer cells.

Prostate cancer kills about 250,000 men a year globally and is the second most common cause of cancer death in men in the United States, after lung cancer.

Since November, Medivation shares have soared on hopes that MDV3100 will be a commercial success.

IN TALKS OVER FDA SUBMISSION

Other serious side effects from MDV3100 included fatigue, cardiac disorders, liver function test abnormalities and myocardial infarction, said Medivation Chief Executive David Hung, noting that all were more prevalent in the placebo group than in the treatment group.

"The number of seizures is too small to make any conclusions as to whether or not there is even a causal relationship," he said.

Hung said Medivation is currently in discussions with the U.S. Food and Drug Administration regarding a new drug application.

Wall Street analysts, on average, have forecast MDV3100 sales of $846 million by 2016, according to Thomson Reuters.

New details of the trial included data showing that 54 percent of MDV3100 patients experienced a 50 percent or more decline in levels of prostate specific antigen, or PSA, while just 1.5 percent of placebo patients saw that much of a drop.

The median time to PSA progression was 8.3 months for the MDV3100 group and 3 months for the placebo patients.

Shrinkage of soft tissue tumors was seen in 28.9 percent of MDV3100 patients, compared with 3.8 percent of placebo patients.

This week's ASCO symposium will also feature full results from a trial of Alpharadin, a prostate cancer drug being developed by Germany's Bayer and Norwegian biotech Algeta.

The drug, which has been granted a fast-track review by U.S. regulators, is designed to deliver minute, highly-charged doses of radiation to secondary tumors in the bone.

Full results of a trial involving patients with advanced prostate cancer that had spread to the bone showed that Alpharadin delayed the time to a first skeletal-related event, including fractures, to 13.6 months, compared with 8.4 months for standard care.

Serious side effects, including anemia, were largely balanced between both arms of the trial.

Wall Street analysts have forecast Alpharadin sales of $485 million by 2016.

(Reporting by Deena Beasley; Editing by Steve Orlofsky, Gary Hill)

Source: http://us.rd.yahoo.com/dailynews/rss/health/*http%3A//news.yahoo.com/s/nm/20120201/hl_nm/us_medivation_prostatecancer

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Wednesday, February 1, 2012

Mexico police rescue 7-year-old locked in school (AP)

MONTERREY, Mexico ? Municipal police say a 7-year-old was locked inside a classroom by his teacher as punishment for supposed misbehavior and left alone for six hours until he was rescued by officers around midnight.

The boy was found under the teacher's desk, covering himself with one of her sweaters for warmth.

Police say the boy's family started looking for him Monday after he didn't return home from school on time. One of the boy's friends said he had been punished by the teacher, so police were eventually called to the school and found the boy.

Education officials say the mother has filed a criminal complaint, and the case is under investigation.

The mother tells MVS Radio that the teacher had abused her son at least once before, by taping him to the legs of a desk.

Source: http://us.rd.yahoo.com/dailynews/rss/latam/*http%3A//news.yahoo.com/s/ap/20120201/ap_on_re_la_am_ca/lt_mexico_child_locked_in_school

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Sarah Palin email hacker loses appeal (Reuters)

(Reuters) ? A former college student convicted for hacking into Sarah Palin's e-mail account during the 2008 presidential election lost a bid to overturn his felony conviction on Monday.

The former University of Tennessee student, David Kernell, argued he was not aware of any pending investigation when he deleted information from his computer related to the hacking of Palin's account. But the U.S. Court of Appeals for the 6th Circuit found Kernell's awareness of a possible future FBI investigation was enough to uphold a conviction on obstruction of justice.

Kernell guessed his way into Palin's Yahoo! account in September 2008, stumbling upon the correct answer to the password security question of where Palin met her spouse. After snooping through Palin's email and taking several screenshots, he changed the account's password and posted it on an Internet message board where he boasted about the breach.

The incident gave rise to one of the most high-profile jury trials in the Eastern District of Tennessee's history, with testimony from Palin and her reality TV star daughter, Bristol Palin. While Kernell claimed the hacking was a college prank, the prosecution painted the breach as a politically motivated attempt to derail the campaign of Palin and her presidential running mate John McCain.

A jury convicted Kernell of a misdemeanor for accessing a protected computer and a felony for destroying records in anticipation of a government investigation. The trial judge sentenced Kernell to a prison term of one year and a day.

Kernell appealed the felony conviction, arguing it was unconstitutional to prosecute someone for destroying records before any official investigation had been launched. He continued the appeal even after he was released in November, after serving less than 11 months.

While the 6th Circuit on Monday recognized the law was both vague and broad, it concluded the law applied directly to Kernell's conduct. In one message-board post, Kernell expressed fears of an FBI investigation. Other evidence showed he deleted his Internet browsing history and cleaned his hard drive to erase any trails of the hacking. That was sufficient evidence of obstructive intent, the court ruled.

Kernell's lawyer Wade Davies said the opinion confirms Kernell had no knowledge of an official investigation at the time of the alleged obstruction. He plans to seek review by the full court of appeals or the Supreme Court on the constitutionality of being convicted for obstructing justice without knowledge of a pending investigation, he said.

The Department of Justice did not immediately respond to a request for comment.

(Editing by Daniel Trotta)

Source: http://us.rd.yahoo.com/dailynews/rss/security/*http%3A//news.yahoo.com/s/nm/20120130/us_nm/us_palin_hacking

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Tuesday, January 31, 2012

Clever Plans to Reform Legal Education Won't Make Legal Services ...

January 30, 2012 12:04 PM

Clever Plans to Reform Legal Education Won't Make Legal Services Any Cheaper

Posted by Matt Leichter

Due to the stream of negative press America's legal education system has received, it is becoming almost a rite of passage for aspiring reformers to submit their own proposals to fix the problem. There's nothing wrong with that, but some proposals are more sophisticated than others. Here are ten examples in no particular order:

? UCLA law professor Stephen Bainbridge recommends unilaterally shutting down the bottom half of the ABA law schools per U.S. News & World Report's rankings.

? Law School Transparency advocates requiring law schools to gather and provide accurate graduate employment data to applicants and letting them decide whether law school is worthwhile.

? Two economists, Clifford Winston and Robert W. Crandall, want to completely deregulate legal services.

? Yale law professors Ahkil Reed Amar and Ian Ayers want first-year law students to be able to demand a partial tuition refund if they choose to discontinue law school. (It should be noted that Southern Illinois law professor Christine Hurt proposed the same idea in 2010).

? Attorney Ari L. Kaplan proposes law schools backload their costs, making the first year cheap so students can decide if they want to continue without significant financial penalty.

? One common suggestion is to turn the third year of law school into an apprenticeship program.

? Scambloggers' views differ,?but generally they advocate eliminating the formal legal education requirement altogether, though some would like the deans incarcerated for fraud.

? CUNY law professor Michael Macchiarola and attorney Arun Abraham argue for law schools to give their graduates "put options" on their student loans, which if exercised would require law schools to reimburse graduates the difference between their projected incomes after ten years and their actual incomes.

? I'd like to see the Direct Loan program dismantled and bankruptcy protections restored to student debt. Legal education can be financed by human capital contracts in which graduates pay roughly 10 percent of their disposable incomes for 10 years back to the law school, providing they're employed using their legal educations.

? And most recently, Northwestern law professor John O. McGinnis and attorney Russell D. Mangas (Kirkland & Ellis) stepped forward on the Wall Street Journal?s opinion page to advocate reducing legal education into an undergraduate major.

All these proposals have their drawbacks, particularly Winston and Crandall's, which I believe uses the plight of underemployed, indebted law grads as a pretext to ram through their neoliberal deregulation agenda.

But I'd like to focus on McGinnis and Mangas' proposal, and not because I disagree with it. Quite the contrary, as far as I'm concerned the test of a reform proposal rests on its ability to allow market demand for legal services to control excess demand for legal education. The current system tries to do it the other way around, resulting in an expensive, pushing-the-string ideology that promotes people paying for education and then letting the market decide whether they get to use it fruitfully. McGinnis' and Mangas' proposal doesn't fully address that, but at least it clearly reduces the education costs lawyers would incur in entering the profession. However, it leans on two premises I believe are false, and importantly, other proposals duplicate them:

(1) There is a shortage of attorneys in the United States.

(2) The costs of legal education raises the cost of legal services.

The first is easy to falsify, the second is more involved.

For specific numbers on lawyers, the ABA recently updated its Web site with a spreadsheet of its "Total National Lawyer Counts," which measures the number of "active and resident" attorneys in the U.S. It's an impressive dataset, though I think the pre-1980 numbers aren?t very accurate and also include non-practicing lawyers who serve as judges, legislators, executives, administrators, etc. The ABA also gives us the number of people who graduated from its law schools each year, which isn't the total number of potential attorneys (aside from the several thousand that have passed away or could never pass a bar exam), but it does represent the majority. Archived issues of the Bureau of Labor Statistics' (BLS) Occupational Outlook Handbook (OOH) provide estimates of the number of employed lawyers between 1994 and 2008. In each edition, the OOH predicts there would be more law graduates looking for work than the number of jobs available for them. I contacted the BLS, and in addition to sending me the Current Population Survey's (CPS) number of employed lawyers going back to 1983, it informed me that the BLS considers the CPS more definitive than the OOH. Here's a comparison against the population going back to 1950, using Census data:

No. Lawyers Per Capita

Given that there were a few years in which the BLS managed to find more employed lawyers than state bar authorities reported as active on their rolls, I suspect the CPS overstates the number of employed lawyers and that the actual number is closer to the OOH's, which is unfortunate given its shallow employment projection for 2018. Nevertheless, it's clear that the lines have been splitting apart for quite some time, a topic I may cover at a future date. True, many potential attorneys could have left the rolls and found gainful employment in other industries, but many more left the profession early in their careers while others never had good chances at creating them. This is the exact opposite of what we would expect to see if there was a shortage of lawyers.

Moving on to the second premise, the cost of legal education's bearing on the cost of legal services, McGinnis and Mangas write:

?[T]he great benefit of the undergraduate option would be lowering the cost of legal education, thus increasing the supply of lawyers willing to charge lower fees.?

The authors assume that lawyers pass their education's costs (especially student loans) onto their clients. Thus, the more unevenly student debt is distributed among lawyers, the more they will have to eat their student loan payments to compete with those who paid less. Here?s what we know about the unevenness of law school debt?s distribution.

(1) As recently as 2010, about 15 percent of all ABA grads finished law school with zero law school debt.

(2) Some law schools are cheaper than others, especially public law schools and those in Puerto Rico, so those who graduate with debt have varying amounts. (Notice that McGinnis voices no concern that Northwestern's graduates will be unemployable when Mangas's firm decides to switch to hiring Northern Illinois or Southern Illinois grads to cut costs.)

(3) Older lawyers frequently have less student debt than more recent grads, so their loan payments are smaller.

(4) Some states allow graduates of cheaper, non-ABA law schools to sit for their bar exams, or they allow people to forgo the legal education requirement altogether.

Additionally, even if debts were evenly distributed, lawyers might still find that offering lower prices offsets the cost of their debt payments with increased business, until others do the same.

The fourth point, though, is critical. California has scores of relatively cheap state-accredited, unaccredited, distance-learning, correspondence, and online law schools. This system is not new, yet none of the reformers who believe cheaper education leads to cheaper lawyers has compared the cost structures of California's legal industry to "ABA-only" states'. Surely by now there are more than enough non-ABA attorneys licensed in California to have made a noticeable difference in the cost of legal services as McGinnis and Mangas argue, yet California?s ABA law schools (including public ones) aren?t competing with non-ABA schools in terms of price. They charge about $40,000 per year in tuition, and they increase it each year over inflation.

Why aren't California's more price-sensitive firms hiring grads directly from the People's College of Law in Los Angeles rather than from UCLA? Better yet, given non-ABA graduates' lower bar passage rates, why aren't firms sending associates to stand around outside LSAT test centers, handing people their business cards and offering to help them through a correspondence program to cut out the ABA middleman? Better yet, they could simply hire people straight out of college (California doesn't even require that much) and have them qualify for the bar by "reading the law," which California allows.

Firms could do this, but instead, they prefer ABA grads from highly regarded law schools. Either California?s legal employers are all monumentally bad businesspeople, or the cost of legal education isn't their (much less their clients') problem.

Let me be clear, McGinnis and Mangas's proposal offers more than some of the others I listed above. But while it would save would-be lawyers time and money, but it still does not ensure that the country's need for legal services determines how many people undergo legal education. Those concerned about providing legal services to the poor will have to demand poverty alleviation and expanded legal aid programs. These solutions politicize the legal profession's role in society, but I think that's unavoidable. More than clever proposals, it will take courage for the profession to admit that noblesse oblige and low-cost education won't entice lawyers to serve the destitute. It will also take courage to admit that law graduates' debts do nothing but reduce their living standards, especially when the profession has no place for them.

Matt Leichter is an attorney licensed in Wisconsin and New York, and he holds a masters in International Affairs from Marquette University. He operates The Law School Tuition Bubble, which archives, chronicles, and analyzes the deteriorating American legal education system. It is also a platform for higher education and student debt reform.

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Source: http://amlawdaily.typepad.com/amlawdaily/2012/01/clever-plans-to-reform-legal-education-wont-make-legal-services-any-cheaper.html

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Canon earnings outlook falters, president steps down (Reuters)

TOKYO (Reuters) ? Canon Inc's 76-year-old chairman and CEO will take on the additional role of president after the $60 billion Japanese camera and printer maker forecast weak earnings growth and said its current president was stepping down.

Like other export-focused Japanese manufacturers, Canon, which makes 80 percent of its revenue overseas, has been hit by a strong yen and a weak economy, on top of last year's floods in Thailand that closed a printer plant and ruptured supply lines.

Canon said Tuneji Uchida, 70, will resign as of March 29, and be replaced by Fujio Mitarai, who served as president from 1995-2006 and has since held the post of chairman.

"Mitarai was at the centre of management, so I don't think there will be any sudden changes," said Naoki Fujiwara, a fund manager at Shinkin Asset Management, which manages about 500 billion yen ($6.5 billion) in assets.

"They do need to hand over to the next generation at some stage, so we're interested to see when that will happen."

Canon forecast 2012 operating profit of 390 billion yen ($5.1 billion), up from last year's 378.1 billion yen, but some way below the average forecast of 470 billion yen from 20 analysts surveyed by Thomson Reuters I/B/E/S.

Profit in 2010 was 387.5 billion yen.

Chief Financial Officer Toshizo Tanaka told reporters on Monday the company would work towards handing over to the next generation over the next three years. For now, given the uncertain economy, choosing a company veteran to replace Uchida, who had asked to step down, was the best option, he said.

Mitarai stepped down as president when he was appointed head of Japan's biggest business lobby, Nippon Keidanren, but he continued to play an active role and was named among the world's 30 best CEOs by Barron's magazine every year between 2008 and 2011.

A nephew of Takeshi Mitarai, among the first executives to head the company, Mitarai joined in 1961 after graduating from law school.

CAUTIOUS OUTLOOK

Canon posted a 14 percent increase in fourth-quarter operating profit, to 94.6 billion yen, in line with consensus estimates, after a fresh round of cost-cutting.

"They're forecasting a rise in 2012 earnings, but given the impact of exchange rates, they're taking a harsh outlook on profits," said Mizuho Research Institute senior economist Koji Takeuchi. "It's not negative overall, but Canon's indication of a cautious view will not be lost on the market."

Canon, which made its first camera in 1933 and now has its IXUS and PowerShot cameras competing against Nikon and Sony Corp, aims to sell 22 million compact cameras and 9.2 million interchangeable lens cameras this year, up from 18.7 million and 7.2 million, respectively, last year.

Nikon said in November it expected to sell 16 million compact cameras in the year to end-March, and 4.7 million digital SLR cameras.

Canon also competes with Xerox in printers.

Xerox lowered its 2012 outlook this month, predicting its business would feel the impact from the European debt crisis.

Canon shares have fallen about 18 percent since the start of last year, slightly underperforming the benchmark Nikkei average's 14 percent decline. The stock closed down 1 percent at 3,435 yen on Monday ahead of the earnings.

($1 = 76.67 yen)

(Reporting by Isabel Reynolds and Takeshi Yoshiike; Editing by Muralikumar Anantharaman, Edwina Gibbs and Ian Geoghegan)

Source: http://us.rd.yahoo.com/dailynews/rss/business/*http%3A//news.yahoo.com/s/nm/20120130/bs_nm/us_canon_results

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